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T.-Y. Lin

 

pin_pi.gif (1013 個位元組) 學歷:

sphere02.gif (209 個位元組) 國立台灣大學動物系學士.

sphere02.gif (209 個位元組) 美國普渡大學化學系博士.

 

pin_pi.gif (1013 個位元組) 經歷:

sphere02.gif (209 個位元組) 麻省理工學院(M.I.T.), Whitehead Institute of Biomedical Research 研究員 .

sphere02.gif (209 個位元組) Brandeis University 研究員 .

 

 

pin_pi.gif (1013 個位元組) 教學課程:

sphere02.gif (209 個位元組)高等生物化學及分子生物學

sphere02.gif (209 個位元組)物理生物化學

sphere02.gif (209 個位元組)高等物理生物化學

sphere02.gif (209 個位元組)普通生物學

sphere02.gif (209 個位元組)普通生物學實驗等

sphere02.gif (209 個位元組)分析化學

sphere02.gif (209 個位元組)生化與藥學之應用

 

 

pin_pi.gif (1013 個位元組) 著作:

sphere02.gif (209 個位元組) Yang, C.-H., Shih, C.-T., Chen, K.-T., Lee, P.-H., Tsai, P.-H., Lin, J.-C., Yen, C.-Y., Lin, T.-Y. & Lu, C.L. 2016. iPARTS2: an improved tool for pairwise alignment of RNA tertiary structures, version 2. Proceedings of the 27th International Conference on Genome Informatics (GIW 2016),  Highlight paper.

sphere02.gif (209 個位元組)Lin, T.-Y. 2016. Simple sequence repeat variations expedite phage divergence: mechanisms of indels and gene mutations. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 789,  48-56.   doi: 10.1016/j.mrfmmm.2016.04.001.

sphere02.gif (209 個位元組)Liu, S.-Y., Liu, I.-C., & Lin, T.-Y. 2016. Truncated Escherichia coli thioredoxin induces proliferation of human blood mononuclear cells and production of reactive oxygen species as well as proinflammatory cytokines. Cell Biochemistry and Function 34,  226-232.  doi: 10.1002/cbf.3180.

sphere02.gif (209 個位元組) Lin, T-Y. 2016. Characterization data of simple sequence repeats of phages closely related to T7M. Data Brief. 8 ,  828-835. doi: 10.1016/j.dib.2016.06.035.

sphere02.gif (209 個位元組)Yang, C.-H., Shih, C.-T., Chen, K.-T., Lee, P.-H., Tsai, P.-H., Lin, J.-C., Yen, C.-Y., Lin, T.-Y., & Lu, C.-L. 2016. iPARTS2: an improved tool for pairwise alignment of RNA tertiary structures, version 2. Nucleic Acids Res. 44(W1),  W328-332. doi: 10.1093/nar/gkw412.

sphere02.gif (209 個位元組)Lin, T.-Y., Lo, Y.-H., Tseng, P.-W., Chang, S.-F., Lin, Y.-T., & Chen, T.-S. 2011. A T3 and T7 Recombinant Phage Acquires Efficient Adsorption and a Broader Host Range: Four-way Junctions at Sites of Recombination. PLoS ONE  7 (2), E30954 (2012).

sphere02.gif (209 個位元組)Lin, T.-Y. 2009. Protein-protein interaction as a powering source of oxidoreductive reactivity. Mol. BioSyst. 6,  1454-1462.

sphere02.gif (209 個位元組)Leu, G.-Z., Lin, T.-Y., & Hsu, J. T.A. 2007. Inhibition of hepatitis virus C replication by arachidonic acid and its peroxidative product. 

sphere02.gif (209 個位元組)Hwang, D.-R., Lin, R.-K., Leu, G.-Z., Lin, T.-Y., Lien, T.-W., Yu, M.-C., Yeh, C.-T., & Hsu, J.T. 2005. Inhibition of Hepatitis C Virus Replication by Antimonial Compounds. Antimicrob. Agents Chemother 49, 4197-4202.

sphere02.gif (209 個位元組)Leu, G.-Z., Lin, T.-Y., & Hsu, J. T.A. 2004. Anti-HCV activities of selective polyunsaturated fatty acids. Biochem. Biophys. Res. Comm. 318, 275-280.

sphere02.gif (209 個位元組)Lin, T.-Y., & Chen, T.-S. 2004. A positive at position 33 of thioredoxin primarily affects its interactions with other proteins but not redox potential. Biochemistry 43, 945-952. 

sphere02.gif (209 個位元組)Lu, S. M. et al. 2001. Predicting the reactivity of proteins from their sequence alone.  Proc. Natl. Acad. Sci., U.S.A. 98, 1410-1415.

sphere02.gif (209 個位元組)Lin, T.-Y.  1999. G33D mutant thioredoxin primarily affects the kinetics of reaction with thioredoxin reductase. Probing the structure of the mutant protein. Biochemistry 38, 15508-15513.

sphere02.gif (209 個位元組)Pasternak, a., Liu, X., Lin, T.-Y., Hedstrom, L. 1998. Activating a zymogen without proteolytic processing: Mutation of Lys15 and Asn194 Activates Trypsinogen. Biochemistry 37, 16201-16210.

sphere02.gif (209 個位元組)Lin, T.-Y., & Timasheff, S. N. 1996. On the role of surface tension in the stabilization of globular proteins. Protein Science 5, 372-381.

sphere02.gif (209 個位元組)Hedstrom, L., Lin, T.-Y., & Fast, W. 1996. Hydrophobic interaction controls zymongen activation in the trypsin family of serine proteases. Biochemistry 35, 4515-4523.

sphere02.gif (209 個位元組)Kita, Y., Arakawa, T., Lin, T.-Y., & Timasheff, S. N., 1994. Contribution of the surface free energy perturbation to protein-solvent interactions. Biochemistry 33, 15178-15189.

sphere02.gif (209 個位元組)Lin, T.-Y., & Timasheff, S.N., 1994. Why do some organisms use a urea-methylamine mixture as osmolyte? Thermodynamic compensation of urea and methylamine N-oxide interactions with protein. Biochemistry 33, 12695-12701.

sphere02.gif (209 個位元組)Musil, D., Bode, W., Huber, R., Laskowki, M., Jr., Lin, T.-Y., & Ardelt, W. 1991. The refined X-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains form Silver Pheasant (OMSVP3*) and from Japanese Quail (OM JPQ3*). J. Mol. Biol. 220, 739-755.

sphere02.gif (209 個位元組)Lin, T.-Y, & Kim, P. S. 1991. Evaluating the effects of a single amino acid substitution on the native and the denatured states of a protein. Proc. Nat1 Acad. Sci-USA 88:10573-10577.

sphere02.gif (209 個位元組)Lin, T.-Y. & Kim, P. S. 1989. Urea dependence of thiol-disulfide equilibria in thioredoxin: Confirmation of the linkage relationship and a sensitive assay for structure. Biochemistry 28, 5282-5287.

sphere02.gif (209 個位元組)Wang, R., Cotter, R. J., Lin, T.-Y., & Laskowski, M., Jr. 1988. Plasma desorption mass spectrometric analysis of glycosylated ovomucoid third domain from Japanese Quail. Rapid communication in mass spectrometry 2, 71-73.

sphere02.gif (209 個位元組)Lin, T.-Y., Cook, J. A., & Laskowski, M., Jr. 1985. HPLC separation of natural mixtures of ovomucoid third domains differing by a single amino acid substitution. Biochemsitry 24, 3385.

 

 

 

我們所做研究的重要性在國際上受到重視並呈現於近年來受到不少邀請於國際型學術會議演講或雜誌書籍發表文章.

 

pin_pi.gif (1013 個位元組) 受邀於國際學術會議演講:

sphere02.gif (209 個位元組)   Honorable speaker invitation for the 4th World Congress on Virology, San Antonio, USA (2014.10. 06-08).

sphere02.gif (209 個位元組)   International Conference and Exhibition on Metabolomics & Systems Biology (2011.11.7邀請函)

sphere02.gif (209 個位元組)   EPS Global International Forum of Analytical Science (2011.11.4邀請函)

sphere02.gif (209 個位元組)“Measurements of Effective Concentration of Thiols in Proteins”, The Third Symposium on Recent Advances in biophysics (1997)

sphere02.gif (209 個位元組)“The Role of Surface Tension in globular Protein Stabilization”, International Symposium on biophysics and structural biology (1995)

 

pin_pi.gif (1013 個位元組) 受邀於書籍期刊發表文章:

sphere02.gif (209 個位元組)   Article or review paper on the topic of protein-protein interactions for the Special Issue entitled "Protein-protein interactions" of the journal Biology (2014.6.27邀請函).

sphere02.gif (209 個位元組)   Review chapter in Advances in Virus Research. iConcept Press Ltd (2012.4.30邀請函)

sphere02.gif (209 個位元組)   Book chapter in Protein Interaction. InTech Publishing Group (2011.6.15邀請函)

 

pin_pi.gif (1013 個位元組) 受邀於雜誌擔任編輯或發表文章:

sphere02.gif (209 個位元組)   Invitation as an editor for Bioinfo Publications Journals (2012.8.8邀請函)

sphere02.gif (209 個位元組)   Invitation to contribute a Research/Review/Editorial article, or become an editorial board member of Enzyme Engineering (2012.2.2邀請函)

sphere02.gif (209 個位元組)   Invitation to submit relevant work to Mol. BioSyst. after submitting the 2010 paper (2010.6.8邀請函)

                                                      

 "I do not know what I may appear to the world; but to myself I seem to have been only like a boy playing on the seashore, and diverting myself in now and then finding a smoother pebble or a prettier shell than ordinary, whilst the great ocean of truth lay all undiscovered before me." ~Sir Isaac Newton, English physicist (1642-1727)