References

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Chang, CW, Yu, YC, Hsieh, YH, Chen, PM, Chao, JI, Yao, CC, Hsiung, CN, Chu, HW, Shen, CY, Cheng, CW* (2016) MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition by repressing its target gene Slug in breast cancer. Oncotarget, 7: 16462-16478.

Yin, KH, Hsieh, YH, Sulake, RS, Wang, SP, Chao, JI*, and Chen, C* (2014) Optimization of the gefitinib analogues with potent anticancer activity. Bioorganic & Medicinal Chemistry Letters, 24: 5247-5250..

Huang, YT, Lin, CI, Chien, PH, Tang, TT, Lin, J, and Chao, JI* (2014) The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colon cancer. Chemico-Biological Interactions, 220:41-50.

Lai, YJ, Lin, CI, Wang, CL, and Chao, JI* (2014) Expression of survivin and p53 modulates honokiol-induced apoptosis in human colon cancer cells. Journal of Cellular Biochemistry, 115:1888-1899.

Yang, CR, Liao, WS, Wu, YH, Murugan , K, Chen, C*, and Chao, JI* (2013) CR108, a novel vitamin K3 derivative induces apoptosis and breast tumor inhibition by reactive oxygen species and mitochondrial dysfunction. Toxicology and Applied Pharmacology, 273: 611-622 

Yu, SY, Liu, HF, Wang, SP, Chang, CC, Tsai, CM, and Chao, JI* (2013) Evidence of securin-mediated resistance of gefitinib-induced apoptosis in human cancer cells. Chemico-Biological Interactions, 203: 412-422.

Tsai, CC, Liu, HF, Hsu, KC, Yang, JM, Chen, C, Liu, KK, Hsu, TS, and Chao, JI* (2011) 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration. Biochemical Pharmacology, 81: 856-865. 

Liu, HF, Hu, HC, and Chao, JI* (2010) Oxaliplatin down-regulates survivin by p38 MAP kinase and proteasome in human colon cancer cells. Chemico-Biological Interactions, 188: 535-545. 

Jiang, RH, Su, WC, Liu, HF, Huang, HS, and Chao, JI* (2010) Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death. Journal of Cellular Biochemistry, 111: 274-283. 

Hsu, TS, Chen, C, Lee PT, Chiu, SJ, Liu, HF, and Chao, JI* (2008) 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound  induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway. Cancer Chemotherapy and Pharmacology, 62: 799-808. 

Liu, HF, Hsiao, PW, and Chao, JI* (2008) Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells. Chemico-Biological Interactions, 176: 48-57. 

Chiu, SJ*, Chao, JI, Lin, YJ, and Hsu, TS (2008) Regulation of gamma-H2AX and securin contribute to apoptosis by oxaliplatin via a p38 mitogen-activated protein kinase -dependent pathway in human colorectal cancer cells. Toxicology Letters, 179: 63-70. 

Chiu, SJ, Hsu, TS, and Chao, JI* (2007) Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation. Chemico-Biological Interactions, 170: 153–161.

Chao, JI*, Su, WC, and Liu, HF (2007) Baicalein induces cancer cell death and proliferation retardation by the inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and AKT. Molecular Cancer Therapeutics, 6: 3039-3048. 

Hsiao, PW, Chang, CC, Liu, HF, Tsai, CM, Chiu, TH, and Chao, JI* (2007) Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells. Toxicology and Applied Pharmacology, 222: 97-104.

Chiu, SJ, Hsu, TS, and Chao, JI* (2006) Opposing securin and p53 protein expression in the oxaliplatin-induced cytotoxicity of human colorectal cancer cells. Toxicology Letters, 167:122-130. 

Chao, JI*, Hsu, SH, and Tsou, TC (2006) Depletion of securin increases arsenite-induced chromosome instability and apoptosis via a p53-independent pathway. Toxicological Sciences, 90: 73-86. 

Chao, JI* and Liu, HF (2006) The blockage of survivin and securin expression increases the cytochalasin B-induced cell death and growth inhibition in human cancer cells. Molecular Pharmacology, 69: 154-164. 

Lin, J, Hsiao, PW, Chiu, TH, and Chao, JI* (2005) Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the cell death and growth inhibition in human colon cancer cells. Biochemical Pharmacology, 70: 658–667. 

Kuo, PC, Liu, HF, and Chao, JI* (2004) Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells. Journal of Biological Chemistry, 279: 55875-55885. 

Chao, JI*, Kuo, PC, and Hsu TS (2004) Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells. Journal of Biological Chemistry, 279: 20267-20276.