Bi-Tzen Juang, Ph.D.
Assistant Professor
Department of Biological Science and Technology
National Chiao Tung University, Taiwan
TEL: 886-3-5712121 ext 59720 (lab) or 56928 (office)
Email: btjuang@nctu.edu.tw
Areas of Investigation:
1. Investigation of epigenetic regulation in the olfactory plasticity in
C. elegans
2. Epigenetic dynamics in a model of Fragile X-associated tremor/ataxia
syndrome in C. elegans
Education:
2001-2005 Ph. D., Department
of Biochemistry, University of Cambridge, UK
2000-2001 M. Phil.,
Department of Biochemistry, University of Cambridge, UK
Research
experience:
2012-2013 Associate Specialist
Department of Cell and
Tissue Biology, University of California, San Francisco, USA
2011-2012 Assistant
Project Scientist
Department of
Psychiatry and Behavioral Sciences, University of California, Davis, USA
2005-2011 Postdoctoral Scholar
Center for
Neuroscience, University of California, Davis, USA
Publications:
Juang, B.-T., Ludwig, A., Benedetti,
K.L., Gu, C., Collins, K., Morales, C., Asundi, A., Wittman,T.,
L’Etoile, N.D., Hagerman, P.J. (2014) Expression of
an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs
olfactory adaptation in Caenorhadbditis elegans. Human Molecular Genetics 23,
4945-4959.
Juang, B.-T., Gu, C., Starnes, L., Palladino,
F., Goga, A., Kennedy, S., L'Etoile,
N.D. (2013) Endogenous nuclear RNAi mediates behavioral adaptation to odor.
Cell 154, 1010-1022.
Krzyzanowski, M.C., Brueggemann, C., Ezak, M.J., Wood, J.F., Michaels, K.L., Jackson, C.A., Juang, B.-T., Collins, K.D., Yu,
M.C., L'Etoile, N.D, Ferkey,
D.M. (2013) The C. elegans cGMP-dependent protein
kinase EGL-4 regulates nociceptive behavioral sensitivity. PLoS
Genetics 9, e1003619.
Lee,
J. I., O’Halloran, D., Eastham-Anderson J.,
Juang, B.-T., Kaye, J. A., Scott
Hamilton, O., Lesch, B., Goga,
A., L’Etoile, N. D. (2010) Nuclear entry of a
cGMP-dependent kinase converts transient into long-lasting olfactory
adaptation. Proc Natl Acad Sci USA 107,
6016-6021.
Juang, B.-T., Izeta, A.,
O’Hare, P., and Luisi, B. F. (2005) Purification and
characterization of the Caenorhadbditis elegans HCF protein and domains of human HCF. Biochemistry 44, 10396-10405.
Lee, J.-W., Chen, C.-L., Juang,
B.-T., Chen, J.-Y., Yang, C.-S., Doong, S.-L. (2000) Elevated expression of thyroid hormone receptor alpha 2 (c-erb A- alpha 2) in nasopharyngeal carcinoma. British
Journal of Cancer 83, 1674-1680.