Bi-Tzen Juang, Ph.D.

Assistant Professor

Department of Biological Science and Technology

National Chiao Tung University, Taiwan

TEL: 886-3-5712121 ext 59720 (lab) or 56928 (office)

Email: btjuang@nctu.edu.tw

Areas of Investigation:

1. Investigation of epigenetic regulation in the olfactory plasticity in C. elegans

2. Epigenetic dynamics in a model of Fragile X-associated tremor/ataxia syndrome in C. elegans

Education:

2001-2005 Ph. D., Department of Biochemistry, University of Cambridge, UK

2000-2001 M. Phil., Department of Biochemistry, University of Cambridge, UK

Research experience:

2012-2013 Associate Specialist

Department of Cell and Tissue Biology, University of California, San Francisco, USA

2011-2012 Assistant Project Scientist

Department of Psychiatry and Behavioral Sciences, University of California, Davis, USA

2005-2011 Postdoctoral Scholar

Center for Neuroscience, University of California, Davis, USA

Publications:

Juang, B.-T., Ludwig, A., Benedetti, K.L., Gu, C., Collins, K., Morales, C., Asundi, A., Wittman,T., L’Etoile, N.D., Hagerman, P.J. (2014) Expression of an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs olfactory adaptation in Caenorhadbditis elegans. Human Molecular Genetics 23, 4945-4959.

Juang, B.-T., Gu, C., Starnes, L., Palladino, F., Goga, A., Kennedy, S., L'Etoile, N.D. (2013) Endogenous nuclear RNAi mediates behavioral adaptation to odor. Cell 154, 1010-1022.

Krzyzanowski, M.C., Brueggemann, C., Ezak, M.J., Wood, J.F., Michaels, K.L., Jackson, C.A., Juang, B.-T., Collins, K.D., Yu, M.C., L'Etoile, N.D, Ferkey, D.M. (2013) The C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivity. PLoS Genetics 9, e1003619.

Lee, J. I., O’Halloran, D., Eastham-Anderson J., Juang, B.-T., Kaye, J. A., Scott Hamilton, O., Lesch, B., Goga, A., L’Etoile, N. D. (2010) Nuclear entry of a cGMP-dependent kinase converts transient into long-lasting olfactory adaptation. Proc Natl Acad Sci USA 107, 6016-6021.

Juang, B.-T., Izeta, A., O’Hare, P., and Luisi, B. F. (2005) Purification and characterization of the Caenorhadbditis elegans HCF protein and domains of human HCF. Biochemistry 44, 10396-10405.

Lee, J.-W., Chen, C.-L., Juang, B.-T., Chen, J.-Y., Yang, C.-S., Doong, S.-L. (2000) Elevated expression of thyroid hormone receptor alpha 2 (c-erb A- alpha 2) in nasopharyngeal carcinoma. British Journal of Cancer 83, 1674-1680.